Production Of Transgenic Animals Notes
Transgene is incorporated into the ES cell by Microinjection By a retro virus By electroporation Transgenic stem cells are grown in vitro.
Production of transgenic animals notes. Then they are inserted into a blastocyst and implanted into a hosts uterus to grow normally. The foreign genes must be transmitted through the germ line so that every cell including germ cells of the animal contains the same modified genetic material. After injecting the DNA the embryo is implanted into the uterus of receptive females.
Transgenic animal technologies have come a long way since the creation of the first transgenic mouse in 1974 Transgenic Mouse 2005. Let us discuss a few of them here. Milk is the secretion of mammary glands that can be collected frequently without causing any harm to the animal.
Transgenic animals are created-To study how genes are regulated and how they affect the normal functions of the body and its development. Transgenic organisms are organisms that are injected with foreign DNA. Studying gene function.
To yield industrial as well as consumer product To research human diseases To produce pharmaceutical products and tissue for implantation. The cells are then incorporated into an embryo at the blastocyst stage of development. Animals that have had their DNA manipulated to possess and express a foreign gene are known as transgenic animals.
Applications of Genetically modified animals. Trans-genesis is important for improving the quality and quantity of milk meat eggs and wool production besides creating drug resistant animals. The first transgenic animal was produced is mice by injecting DNA to mouse embryos then implanting the embryos in female mice.
Transgenic mice are developed by injecting DNA into the oocytes or 1-2 celled embryos taken from female mice. Transgenic animals produced with the purpose of producing better and good quality breed increased in milk yield as well as to produce organs to meet the demand for organ transplantation. Due to the controversial concept of cloning and scientific testing on animals there are many questions that revolve around this topic.
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